ZYMOX Oratene Toothpaste Gel provides a safe, healthy way to conveniently clean pet's teeth and freshen breath without brushing. Especially beneficial to those pets on medications, diagnosed with cancer or diabetes, or those with dry mouth in need of gentle, non-drying everyday oral care.Â Oratene contains two patented, natural enzyme systems based on 35 years of enzyme technology that inhibit odor-causing bacteria and remove plaque biofilm. Does not contain Xylitol, alcohol, chlorhexidine or detergent.Â Apply a 1.5" strip to gums once or twice daily. Best if used in the morning, night or after meals. 2.5 Ounces. Made in the USA. Animal and cruelty-free product.